Using Moodle to complete coursework isn't always a walk in the park for a lot of learners, depending on the course content, design and relative online learning experience of your students.
One way to facilitate understanding of where to go, what to do (and how) for your learners is to create a unit walk through resource for each Moodle unit/topic block. You could do this with text and images, but I've found that an audio-visual resource like a screencast gets things across in the most dynamic and effective way.
Here is an example unit walk through video I've just finished as part of a new Moodle course:
That's fine, and perhaps that's all the learners will need. We could create a link to this video at the start of the unit it applies to, perhaps supported via a direct email with the same link.
However, I've generally found it's better to go a bit further than just showing an instructional video. I feature my unit walk through as an introductory 'assignment' that learners need to complete before engaging with the main unit materials. They need to take notes about the video to help them pay more specific attention to it, and to show me just what each learner has understood about what they need to do in the unit.
This process can help answer a lot of questions or misunderstandings before learners get into their coursework, and it helps me target the students who need more specific or hands on assistance.
Here's how I do that in Moodle using the Lesson -> Essay Question function (basically, access to the unit walk through an embedded video and some prompts in 'essay mode' for the learners to take notes or ask questions in response to:
If you're curious about the screencast angle here, I've got an extensive tutorial on how to make screencasts elsewhere on this blog.
Good luck with it!
All of my Moodle tutorials are available in an ongoing bank of resources featured here.